{"id":1552,"date":"2024-09-26T18:28:52","date_gmt":"2024-09-26T22:28:52","guid":{"rendered":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/chapter\/infections-2\/"},"modified":"2024-09-26T19:33:32","modified_gmt":"2024-09-26T23:33:32","slug":"infections","status":"publish","type":"chapter","link":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/chapter\/infections\/","title":{"raw":"2.2 Infections","rendered":"2.2 Infections"},"content":{"raw":"<h1>What Is an Infection?<\/h1>\r\nAn [pb_glossary id=\"520\"]infection[\/pb_glossary] is any illness caused by the growth of a [pb_glossary id=\"521\"]pathogen[\/pb_glossary] on, or in, a person. These pathogens can be [pb_glossary id=\"524\"]bacteria[\/pb_glossary], [pb_glossary id=\"523\"]viruses[\/pb_glossary], or [pb_glossary id=\"522\"]fungi[\/pb_glossary]. The common cold is caused by a virus, and so is influenza (the flu), and COVID-19.\r\n\r\nInfections can range from fairly minor, like coughs and colds, to more serious ones, like septicemia (blood poisoning) and wound infections. Infections can spread quickly unless certain measures are taken.\r\n\r\n[caption id=\"attachment_51\" align=\"aligncenter\" width=\"201\"]<img class=\"wp-image-47 size-medium\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/hand-person-winter-people-girl-woman-1079549-pxhere.com-scaled-1.jpg\" alt=\"\" width=\"201\" height=\"300\" \/> <strong>Figure 2.2.1<\/strong> Infections spread quickly![\/caption]\r\n\r\nWhen a pathogen is commonly found on our body without causing an illness, we call it colonization. People who are colonized will have no signs or symptoms; they feel fine. In certain circumstances, pathogens may go further to cause an infection. For example, <em>Escherichia coli (E. coli)<\/em> is a common species of bacteria found naturally in the intestine, where it helps produce vitamins K and B. While most strains of <em>E. coli<\/em> are harmless to humans, they can cause gastrointestinal problems like diarrhea, and in more severe cases, bacterial meningitis or pneumonia.\r\n\r\nSome people are more at risk for infection because their immune systems are weakened. Clients with certain health conditions \u2014 those with diabetes, heart and skin diseases, or those with a weaker immune system \u2014 are also more at risk for infections.\r\n\r\n&nbsp;\r\n\r\n[caption id=\"attachment_51\" align=\"aligncenter\" width=\"300\"]<img class=\"wp-image-48 size-medium\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/red-blue-pink-close-facial-expression-lip-937257-pxhere.com-scaled-1.jpg\" alt=\"\" width=\"300\" height=\"200\" \/> <strong>Figure 2.2.2 <\/strong>School sores, or impetigo, is highly contagious[\/caption]\r\n<h2 style=\"font-weight: 400;\"><span class=\"TextRun MacChromeBold SCXW94795189 BCX9\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW94795189 BCX9\" data-ccp-parastyle=\"heading 4\">Resident<\/span> <span class=\"NormalTextRun SCXW94795189 BCX9\" data-ccp-parastyle=\"heading 4\">and<\/span> <span class=\"NormalTextRun SCXW94795189 BCX9\" data-ccp-parastyle=\"heading 4\">Transient<\/span> <span class=\"NormalTextRun SCXW94795189 BCX9\" data-ccp-parastyle=\"heading 4\">Flora<\/span><\/span><span class=\"EOP SCXW94795189 BCX9\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:759,&quot;335559738&quot;:59,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/h2>\r\n<div style=\"font-weight: 400;\">\r\n\r\n[caption id=\"attachment_49\" align=\"alignright\" width=\"300\"]<img class=\"wp-image-49 size-medium\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/plant-leaf-flower-petal-pattern-green-718582-pxhere.com_.jpg\" alt=\"\" width=\"300\" height=\"214\" \/> <strong>Figure 2.2.3<\/strong> Bacteria infection[\/caption]\r\n<p style=\"text-align: left;\"><strong><span class=\"TextRun MacChromeBold SCXW209590618 BCX9\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">Not<\/span> a<span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">ll<\/span> g<span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">erms<\/span> c<span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">ause<\/span> i<span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">nfections!<\/span><\/span> <\/strong><span style=\"font-size: 14pt;\">Billions of bacteria live in or on our bodies. This is normal and healthy, as these germs are part of the body\u2019s resident flora. The parts of the body they typically colonize include the surface of the skin, mucous membranes (eyes, nose, mouth), digestive tract (gut, bowel), and upper respiratory system (mouth, nose and throat). These pathogens do not cause harm.<\/span><\/p>\r\n\r\n<\/div>\r\n<p style=\"text-align: left;\">Transient flora<span style=\"text-align: initial; font-size: 1em;\"> are just passing through. Although they may attempt to colonize the same areas of the body as the resident flora, transient germs cannot remain in the <\/span><span style=\"text-align: initial; font-size: 1em;\">body for extended periods.\u00a0<\/span><\/p>\r\n<p style=\"text-align: left;\"><span style=\"text-align: initial; font-size: 1em;\">This is due to:\u00a0<\/span><\/p>\r\n\r\n<ul>\r\n \t<li>Competition from resident flora<\/li>\r\n \t<li>Elimination by the body\u2019s immune system<\/li>\r\n \t<li>Physical or chemical changes within the body that discourage the growth of transient germs<\/li>\r\n<\/ul>\r\n<h2 style=\"font-weight: 400;\">How Infections Occur<\/h2>\r\nUnder normal conditions, neither resident nor transient pathogens cause harm. However, if the opportunity arises, some of these pathogens are able to cause infections. This can happen due to various conditions, including:\r\n<ul style=\"font-weight: 400;\">\r\n \t<li style=\"text-align: justify;\">When the immune system isn\u2019t working properly, normal flora can overpopulate or move into areas of the body where they do not normally live.<\/li>\r\n \t<li style=\"text-align: justify;\">When the balance of normal pathogens is disrupted \u2014 for example, when a person takes broad-spectrum antibiotics \u2014 transient pathogens that are usually crowded out by resident pathogens have an <span style=\"text-align: initial; font-size: 1em;\">opportunity to take over. Tougher, or antibiotic-resistant bacteria, can get the upper hand.<\/span><\/li>\r\n \t<li style=\"text-align: justify;\">Disease can result when normal flora can enter an area of the body that they do not normally get into. Catheters or surgical wounds can allow pathogens into areas of the body that are normally sterile.<\/li>\r\n<\/ul>\r\n[caption id=\"attachment_51\" align=\"aligncenter\" width=\"300\"]<img class=\"wp-image-50 size-medium\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/cold-winter-medicine-health-hot-pharmacy-566564-pxhere.com-scaled-1.jpg\" alt=\"\" width=\"300\" height=\"200\" \/> <strong>Figure 2.2.4<\/strong> Antibiotics can disrupt the balance of normal pathogens[\/caption]\r\n<h2 style=\"font-weight: 400;\">Chain of Infection<\/h2>\r\n<p style=\"text-align: left;\">The chain of infection is a way of describing how an infection spreads from one person to another. Let\u2019s say an infectious germ is living and multiplying in a person. The person coughs into their hand, then touches a door handle, leaving pathogens there. Another person touches the door handle, then touches their eyes, nose, or mouth. The pathogens have just found a way into the next person, completing the chain of infection.<\/p>\r\n\r\n<h2 style=\"font-weight: 400;\">Breaking the Chain of Infection<\/h2>\r\n<p style=\"text-align: left;\">The development of an infection involves a set of complex interrelationships between the source of the [pb_glossary id=\"466\"]microorganism[\/pb_glossary], the susceptible host, and the environment. For infection to occur, it requires the transmission of microorganisms from the source to a susceptible host. One way to understand this complex connection is the chain of infection, which can have six links: the infectious agent, reservoir, portal of exit, mode of transmission, portal of entry and susceptible host (see Figure 2.2.5). Breaking any one of the links in the chain of infection will prevent infection from occurring.<\/p>\r\n\r\n[caption id=\"attachment_51\" align=\"aligncenter\" width=\"600\"]<img class=\"wp-image-51\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/Screenshot-2023-01-22-at-1.33.17-PM.png\" alt=\"\" width=\"600\" height=\"271\" \/> <a id=\"Fig2_2_5\"><\/a> <strong>Figure 2.2.5a and 2.2.5b<\/strong> The chain of infection. (Image courtesy of Public Health Agency of Canada (2016]). [<a class=\"internal\" href=\"#LongDesc2_2_5\">Long description<\/a>][\/caption]\r\n<div class=\"textbox textbox--exercises\"><header class=\"textbox__header\">\r\n<p class=\"textbox__title\">Critical Thinking Question<\/p>\r\n\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n\r\nWhat are some ways you could break the chain of infection and thereby reduce your chances of infection?\r\n\r\n<\/div>\r\n<\/div>\r\n<div class=\"textbox\"><header class=\"textbox__header\">Review Questions\u00a0<\/header>\r\n<div class=\"h5p\">[h5p id=\"2\"]<\/div>\r\n<div class=\"pdf\">\r\n\r\nMatch the words with the chain of infection:\r\n<ol>\r\n \t<li>Mode of transmission:<\/li>\r\n \t<li>Pathogen:<\/li>\r\n \t<li>Portal of entry:<\/li>\r\n \t<li>Portal of exit:<\/li>\r\n \t<li>Reservoir:<\/li>\r\n \t<li>Susceptible host:<\/li>\r\n<\/ol>\r\nOptions:\r\n<ol type=\"a\">\r\n \t<li>Direct contact, air, medical instruments, other objects, other vectors<\/li>\r\n \t<li>Bodily fluids, respiratory droplets<\/li>\r\n \t<li>People, inanimate objects<\/li>\r\n \t<li>Microorganisms, such as bacteria, fungi, viruses, prions, protozoa, worms<\/li>\r\n \t<li>Client, health care worker<\/li>\r\n \t<li>Open wounded, nasal cavity, mucus membranes<\/li>\r\n<\/ol>\r\n<\/div>\r\n<\/div>\r\n<h3>Image descriptions<\/h3>\r\n<a id=\"LongDesc2_2_5\" class=\"internal\"><\/a><strong>Figure 2.2.5a and 2.2.5b The chain of infection<\/strong>\r\n\r\nFigure 2.2.5a shows the chain of infection, a framework for understanding the complex relationship between infection and host during transmission. The chain can have six links: the infection agent, reservoir, portal of exit, mode of transmission, portal of entry and susceptible host.\r\n\r\nFigure 2.2.5b shows that breaking any of the links in the chain of infection, as shown in Figure 2.2.5a, will prevent an infection from occurring.\r\n\r\n[Back to <a class=\"internal\" href=\"#Fig2_2_5\">Figure 2.2.5<\/a>]","rendered":"<h1>What Is an Infection?<\/h1>\n<p>An <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_1552_520\">infection<\/a> is any illness caused by the growth of a <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_1552_521\">pathogen<\/a> on, or in, a person. These pathogens can be <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_1552_524\">bacteria<\/a>, <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_1552_523\">viruses<\/a>, or <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_1552_522\">fungi<\/a>. The common cold is caused by a virus, and so is influenza (the flu), and COVID-19.<\/p>\n<p>Infections can range from fairly minor, like coughs and colds, to more serious ones, like septicemia (blood poisoning) and wound infections. Infections can spread quickly unless certain measures are taken.<\/p>\n<figure id=\"attachment_51\" aria-describedby=\"caption-attachment-51\" style=\"width: 201px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-47 size-medium\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/hand-person-winter-people-girl-woman-1079549-pxhere.com-scaled-1.jpg\" alt=\"\" width=\"201\" height=\"300\" \/><figcaption id=\"caption-attachment-51\" class=\"wp-caption-text\"><strong>Figure 2.2.1<\/strong> Infections spread quickly!<\/figcaption><\/figure>\n<p>When a pathogen is commonly found on our body without causing an illness, we call it colonization. People who are colonized will have no signs or symptoms; they feel fine. In certain circumstances, pathogens may go further to cause an infection. For example, <em>Escherichia coli (E. coli)<\/em> is a common species of bacteria found naturally in the intestine, where it helps produce vitamins K and B. While most strains of <em>E. coli<\/em> are harmless to humans, they can cause gastrointestinal problems like diarrhea, and in more severe cases, bacterial meningitis or pneumonia.<\/p>\n<p>Some people are more at risk for infection because their immune systems are weakened. Clients with certain health conditions \u2014 those with diabetes, heart and skin diseases, or those with a weaker immune system \u2014 are also more at risk for infections.<\/p>\n<p>&nbsp;<\/p>\n<figure id=\"attachment_51\" aria-describedby=\"caption-attachment-51\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-48 size-medium\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/red-blue-pink-close-facial-expression-lip-937257-pxhere.com-scaled-1.jpg\" alt=\"\" width=\"300\" height=\"200\" \/><figcaption id=\"caption-attachment-51\" class=\"wp-caption-text\"><strong>Figure 2.2.2 <\/strong>School sores, or impetigo, is highly contagious<\/figcaption><\/figure>\n<h2 style=\"font-weight: 400;\"><span class=\"TextRun MacChromeBold SCXW94795189 BCX9\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW94795189 BCX9\" data-ccp-parastyle=\"heading 4\">Resident<\/span> <span class=\"NormalTextRun SCXW94795189 BCX9\" data-ccp-parastyle=\"heading 4\">and<\/span> <span class=\"NormalTextRun SCXW94795189 BCX9\" data-ccp-parastyle=\"heading 4\">Transient<\/span> <span class=\"NormalTextRun SCXW94795189 BCX9\" data-ccp-parastyle=\"heading 4\">Flora<\/span><\/span><span class=\"EOP SCXW94795189 BCX9\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559685&quot;:759,&quot;335559738&quot;:59,&quot;335559739&quot;:0,&quot;335559740&quot;:240}\">\u00a0<\/span><\/h2>\n<div style=\"font-weight: 400;\">\n<figure id=\"attachment_49\" aria-describedby=\"caption-attachment-49\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-49 size-medium\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/plant-leaf-flower-petal-pattern-green-718582-pxhere.com_.jpg\" alt=\"\" width=\"300\" height=\"214\" \/><figcaption id=\"caption-attachment-49\" class=\"wp-caption-text\"><strong>Figure 2.2.3<\/strong> Bacteria infection<\/figcaption><\/figure>\n<p style=\"text-align: left;\"><strong><span class=\"TextRun MacChromeBold SCXW209590618 BCX9\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">Not<\/span> a<span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">ll<\/span> g<span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">erms<\/span> c<span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">ause<\/span> i<span class=\"NormalTextRun SCXW209590618 BCX9\" data-ccp-parastyle=\"heading 2\">nfections!<\/span><\/span> <\/strong><span style=\"font-size: 14pt;\">Billions of bacteria live in or on our bodies. This is normal and healthy, as these germs are part of the body\u2019s resident flora. The parts of the body they typically colonize include the surface of the skin, mucous membranes (eyes, nose, mouth), digestive tract (gut, bowel), and upper respiratory system (mouth, nose and throat). These pathogens do not cause harm.<\/span><\/p>\n<\/div>\n<p style=\"text-align: left;\">Transient flora<span style=\"text-align: initial; font-size: 1em;\"> are just passing through. Although they may attempt to colonize the same areas of the body as the resident flora, transient germs cannot remain in the <\/span><span style=\"text-align: initial; font-size: 1em;\">body for extended periods.\u00a0<\/span><\/p>\n<p style=\"text-align: left;\"><span style=\"text-align: initial; font-size: 1em;\">This is due to:\u00a0<\/span><\/p>\n<ul>\n<li>Competition from resident flora<\/li>\n<li>Elimination by the body\u2019s immune system<\/li>\n<li>Physical or chemical changes within the body that discourage the growth of transient germs<\/li>\n<\/ul>\n<h2 style=\"font-weight: 400;\">How Infections Occur<\/h2>\n<p>Under normal conditions, neither resident nor transient pathogens cause harm. However, if the opportunity arises, some of these pathogens are able to cause infections. This can happen due to various conditions, including:<\/p>\n<ul style=\"font-weight: 400;\">\n<li style=\"text-align: justify;\">When the immune system isn\u2019t working properly, normal flora can overpopulate or move into areas of the body where they do not normally live.<\/li>\n<li style=\"text-align: justify;\">When the balance of normal pathogens is disrupted \u2014 for example, when a person takes broad-spectrum antibiotics \u2014 transient pathogens that are usually crowded out by resident pathogens have an <span style=\"text-align: initial; font-size: 1em;\">opportunity to take over. Tougher, or antibiotic-resistant bacteria, can get the upper hand.<\/span><\/li>\n<li style=\"text-align: justify;\">Disease can result when normal flora can enter an area of the body that they do not normally get into. Catheters or surgical wounds can allow pathogens into areas of the body that are normally sterile.<\/li>\n<\/ul>\n<figure id=\"attachment_51\" aria-describedby=\"caption-attachment-51\" style=\"width: 300px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-50 size-medium\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/cold-winter-medicine-health-hot-pharmacy-566564-pxhere.com-scaled-1.jpg\" alt=\"\" width=\"300\" height=\"200\" \/><figcaption id=\"caption-attachment-51\" class=\"wp-caption-text\"><strong>Figure 2.2.4<\/strong> Antibiotics can disrupt the balance of normal pathogens<\/figcaption><\/figure>\n<h2 style=\"font-weight: 400;\">Chain of Infection<\/h2>\n<p style=\"text-align: left;\">The chain of infection is a way of describing how an infection spreads from one person to another. Let\u2019s say an infectious germ is living and multiplying in a person. The person coughs into their hand, then touches a door handle, leaving pathogens there. Another person touches the door handle, then touches their eyes, nose, or mouth. The pathogens have just found a way into the next person, completing the chain of infection.<\/p>\n<h2 style=\"font-weight: 400;\">Breaking the Chain of Infection<\/h2>\n<p style=\"text-align: left;\">The development of an infection involves a set of complex interrelationships between the source of the <a class=\"glossary-term\" aria-haspopup=\"dialog\" aria-describedby=\"definition\" href=\"#term_1552_466\">microorganism<\/a>, the susceptible host, and the environment. For infection to occur, it requires the transmission of microorganisms from the source to a susceptible host. One way to understand this complex connection is the chain of infection, which can have six links: the infectious agent, reservoir, portal of exit, mode of transmission, portal of entry and susceptible host (see Figure 2.2.5). Breaking any one of the links in the chain of infection will prevent infection from occurring.<\/p>\n<figure id=\"attachment_51\" aria-describedby=\"caption-attachment-51\" style=\"width: 600px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-51\" src=\"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-content\/uploads\/sites\/430\/2024\/09\/Screenshot-2023-01-22-at-1.33.17-PM.png\" alt=\"\" width=\"600\" height=\"271\" \/><figcaption id=\"caption-attachment-51\" class=\"wp-caption-text\"><a id=\"Fig2_2_5\"><\/a> <strong>Figure 2.2.5a and 2.2.5b<\/strong> The chain of infection. (Image courtesy of Public Health Agency of Canada (2016]). [<a class=\"internal\" href=\"#LongDesc2_2_5\">Long description<\/a>]<\/figcaption><\/figure>\n<div class=\"textbox textbox--exercises\">\n<header class=\"textbox__header\">\n<p class=\"textbox__title\">Critical Thinking Question<\/p>\n<\/header>\n<div class=\"textbox__content\">\n<p>What are some ways you could break the chain of infection and thereby reduce your chances of infection?<\/p>\n<\/div>\n<\/div>\n<div class=\"textbox\">\n<header class=\"textbox__header\">Review Questions\u00a0<\/header>\n<div class=\"h5p\">\n<div id=\"h5p-2\">\n<div class=\"h5p-iframe-wrapper\"><iframe id=\"h5p-iframe-2\" class=\"h5p-iframe\" data-content-id=\"2\" style=\"height:1px\" src=\"about:blank\" frameBorder=\"0\" scrolling=\"no\" title=\"Drag words Ch 2.4\"><\/iframe><\/div>\n<\/div>\n<\/div>\n<div class=\"pdf\">\n<p>Match the words with the chain of infection:<\/p>\n<ol>\n<li>Mode of transmission:<\/li>\n<li>Pathogen:<\/li>\n<li>Portal of entry:<\/li>\n<li>Portal of exit:<\/li>\n<li>Reservoir:<\/li>\n<li>Susceptible host:<\/li>\n<\/ol>\n<p>Options:<\/p>\n<ol type=\"a\">\n<li>Direct contact, air, medical instruments, other objects, other vectors<\/li>\n<li>Bodily fluids, respiratory droplets<\/li>\n<li>People, inanimate objects<\/li>\n<li>Microorganisms, such as bacteria, fungi, viruses, prions, protozoa, worms<\/li>\n<li>Client, health care worker<\/li>\n<li>Open wounded, nasal cavity, mucus membranes<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<h3>Image descriptions<\/h3>\n<p><a id=\"LongDesc2_2_5\" class=\"internal\"><\/a><strong>Figure 2.2.5a and 2.2.5b The chain of infection<\/strong><\/p>\n<p>Figure 2.2.5a shows the chain of infection, a framework for understanding the complex relationship between infection and host during transmission. The chain can have six links: the infection agent, reservoir, portal of exit, mode of transmission, portal of entry and susceptible host.<\/p>\n<p>Figure 2.2.5b shows that breaking any of the links in the chain of infection, as shown in Figure 2.2.5a, will prevent an infection from occurring.<\/p>\n<p>[Back to <a class=\"internal\" href=\"#Fig2_2_5\">Figure 2.2.5<\/a>]<\/p>\n<div class=\"glossary\"><span class=\"screen-reader-text\" id=\"definition\">definition<\/span><template id=\"term_1552_520\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_1552_520\"><div tabindex=\"-1\"><p>The invasion of the body tissues by pathogens, allowing them to multiply and cause a reaction of the immune system to their presence of the toxins they produce.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_1552_521\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_1552_521\"><div tabindex=\"-1\"><p>A microorganism, such as a virus, bacterium, or fungus, that can cause disease.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_1552_524\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_1552_524\"><div tabindex=\"-1\"><p>Single-cell microorganisms that are typically a few micrometres in length and have several shapes, ranging from spheres to rods and spirals. Bacteria are present in most habitats, including soil and water. In the human body, bacteria outnumber human cells ten to one. The majority of them do not make us sick; in fact, our bodies give them a place to live, and many of them keep us alive.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_1552_523\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_1552_523\"><div tabindex=\"-1\"><p>Infectious agents that reproduce inside the living cells of other organisms. They are unable to reproduce on their own but require the mechanisms of living cells to do so. Examples are influenza or COVID-19 in humans.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_1552_522\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_1552_522\"><div tabindex=\"-1\"><p>A member of a large group of organisms that includes microorganisms such as yeasts, moulds, mushrooms. Many fungi (mainly yeasts and moulds) live in our environment and on our bodies. Most of the organisms don\u2019t cause illness unless they can invade areas where they are not normally found, such as in the lungs or under the skin.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><template id=\"term_1552_466\"><div class=\"glossary__definition\" role=\"dialog\" data-id=\"term_1552_466\"><div tabindex=\"-1\"><p>Microscopic, sometimes single-cell organisms including bacteria, fungi and viruses. A small proportion are pathogenic, meaning they can cause disease.<\/p>\n<\/div><button><span aria-hidden=\"true\">&times;<\/span><span class=\"screen-reader-text\">Close definition<\/span><\/button><\/div><\/template><\/div>","protected":false},"author":123,"menu_order":2,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[50],"contributor":[],"license":[],"class_list":["post-1552","chapter","type-chapter","status-publish","hentry","chapter-type-numberless"],"part":43,"_links":{"self":[{"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/pressbooks\/v2\/chapters\/1552","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/wp\/v2\/users\/123"}],"version-history":[{"count":2,"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/pressbooks\/v2\/chapters\/1552\/revisions"}],"predecessor-version":[{"id":1861,"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/pressbooks\/v2\/chapters\/1552\/revisions\/1861"}],"part":[{"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/pressbooks\/v2\/parts\/43"}],"metadata":[{"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/pressbooks\/v2\/chapters\/1552\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/wp\/v2\/media?parent=1552"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/pressbooks\/v2\/chapter-type?post=1552"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/wp\/v2\/contributor?post=1552"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/opentextbc.ca\/hcalabtheoryandpractice\/wp-json\/wp\/v2\/license?post=1552"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}