{"id":175,"date":"2019-10-17T19:31:13","date_gmt":"2019-10-17T23:31:13","guid":{"rendered":"https:\/\/opentextbc.ca\/nursingpharmacology\/chapter\/4-7-muscarinic-receptor-agonist\/"},"modified":"2023-08-01T14:29:09","modified_gmt":"2023-08-01T18:29:09","slug":"4-7-muscarinic-receptor-agonist","status":"publish","type":"chapter","link":"https:\/\/opentextbc.ca\/nursingpharmacology\/chapter\/4-7-muscarinic-receptor-agonist\/","title":{"raw":"4.7 Muscarinic Receptor Agonists","rendered":"4.7 Muscarinic Receptor Agonists"},"content":{"raw":"Pilocarpine is a muscarinic receptor agonist.\r\n\r\n<strong>Mechanism of Action:<\/strong> Pilocarpine causes the ciliary muscle to contract, allowing for the drainage of aqueous humor from the anterior chamber of the eye and reducing intraocular pressure related to glaucoma.\r\n\r\n<strong>Indications for Use:<\/strong> Pilocarpine is used to treat glaucoma.\r\n\r\n<strong>Nursing Considerations Across the Lifespan:\u00a0<\/strong>Muscarinic receptor agonists, such as pilocarpine, can be used in children and older adults. There are no necessary dose adjustments for kidney or liver dysfunction in older adults.\r\n\r\nRemove contact lens before administration. Apply light finger pressure on lacrimal sac for 2 minutes after instilling to minimize systemic absorption.\r\n\r\n<strong>Patient Teaching &amp; Education:<\/strong>\u00a0 Advise the client to use caution with night driving.\u00a0 Additionally, use of this medication can cause hypotension.[footnote]uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]\r\n<h1>Pilocarpine Medication Card<\/h1>\r\nNow let's take a closer look at the medication card on pilocarpine.[footnote]This work is a derivative of <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" rel=\"noopener noreferrer\">Daily Med<\/a> by <a href=\"https:\/\/www.nlm.nih.gov\/\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a class=\"internal\" href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" rel=\"noopener noreferrer\">public domain<\/a>.[\/footnote] Because information about medication is constantly changing, nurses should always consult evidence-based resources to review current recommendations before administering specific medication.\r\n<div class=\"textbox textbox--learning-objectives\"><header class=\"textbox__header\">\r\n<h2 class=\"textbox__title\">Medication Card 4.7.1: Pilocarpine<\/h2>\r\n<\/header>\r\n<div class=\"textbox__content\">\r\n\r\n<strong>Class: <\/strong>Muscarinic Agonist\r\n\r\n<strong>Prototypes: <\/strong>pilocarpine\r\n<h3>Therapeutic Effects<\/h3>\r\n<ul>\r\n \t<li>Controls intraocular pressure in glaucoma<\/li>\r\n<\/ul>\r\n<h3>Administration<\/h3>\r\n<ul>\r\n \t<li>Remove contact lens before administration<\/li>\r\n \t<li>Apply light finger pressure on lacrimal sac for 2 minutes after instilling to minimize systemic absorption<\/li>\r\n<\/ul>\r\n<h3>Indications<\/h3>\r\n<ul>\r\n \t<li>Management of intraocular pressure in glaucoma<\/li>\r\n<\/ul>\r\n<h3>Side Effects<\/h3>\r\n<ul>\r\n \t<li>Caution client with night driving as medication can decrease visual acuity<\/li>\r\n<\/ul>\r\n<h3>Nursing Considerations<\/h3>\r\n<ul>\r\n \t<li>Apply pressure on lacrimal sac after instilling<\/li>\r\n<\/ul>\r\n[caption id=\"attachment_1134\" align=\"aligncenter\" width=\"587\"]<img class=\"wp-image-1134 size-full\" src=\"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/397\/2019\/10\/Picture1.jpg\" alt=\"\" width=\"587\" height=\"319\" \/> Figure 4.7a[\/caption]\r\n\r\n<\/div>\r\n<\/div>\r\n<h3>Media Attributions<\/h3>\r\n<ul>\r\n \t<li>Figure 4.7a: Lacrimal Sac by OpenStax Microbiology is licensed under a <a class=\"internal\" href=\"https:\/\/creativecommons.org\/licenses\/by\/2.0\/\" rel=\"noopener\">CC BY 2.0 licence<\/a>.<\/li>\r\n<\/ul>","rendered":"<p>Pilocarpine is a muscarinic receptor agonist.<\/p>\n<p><strong>Mechanism of Action:<\/strong> Pilocarpine causes the ciliary muscle to contract, allowing for the drainage of aqueous humor from the anterior chamber of the eye and reducing intraocular pressure related to glaucoma.<\/p>\n<p><strong>Indications for Use:<\/strong> Pilocarpine is used to treat glaucoma.<\/p>\n<p><strong>Nursing Considerations Across the Lifespan:\u00a0<\/strong>Muscarinic receptor agonists, such as pilocarpine, can be used in children and older adults. There are no necessary dose adjustments for kidney or liver dysfunction in older adults.<\/p>\n<p>Remove contact lens before administration. Apply light finger pressure on lacrimal sac for 2 minutes after instilling to minimize systemic absorption.<\/p>\n<p><strong>Patient Teaching &amp; Education:<\/strong>\u00a0 Advise the client to use caution with night driving.\u00a0 Additionally, use of this medication can cause hypotension.<a class=\"footnote\" title=\"uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral\" id=\"return-footnote-175-1\" href=\"#footnote-175-1\" aria-label=\"Footnote 1\"><sup class=\"footnote\">[1]<\/sup><\/a><\/p>\n<h1>Pilocarpine Medication Card<\/h1>\n<p>Now let&#8217;s take a closer look at the medication card on pilocarpine.<a class=\"footnote\" title=\"This work is a derivative of Daily Med by U.S. National Library of Medicine in the public domain.\" id=\"return-footnote-175-2\" href=\"#footnote-175-2\" aria-label=\"Footnote 2\"><sup class=\"footnote\">[2]<\/sup><\/a> Because information about medication is constantly changing, nurses should always consult evidence-based resources to review current recommendations before administering specific medication.<\/p>\n<div class=\"textbox textbox--learning-objectives\">\n<header class=\"textbox__header\">\n<h2 class=\"textbox__title\">Medication Card 4.7.1: Pilocarpine<\/h2>\n<\/header>\n<div class=\"textbox__content\">\n<p><strong>Class: <\/strong>Muscarinic Agonist<\/p>\n<p><strong>Prototypes: <\/strong>pilocarpine<\/p>\n<h3>Therapeutic Effects<\/h3>\n<ul>\n<li>Controls intraocular pressure in glaucoma<\/li>\n<\/ul>\n<h3>Administration<\/h3>\n<ul>\n<li>Remove contact lens before administration<\/li>\n<li>Apply light finger pressure on lacrimal sac for 2 minutes after instilling to minimize systemic absorption<\/li>\n<\/ul>\n<h3>Indications<\/h3>\n<ul>\n<li>Management of intraocular pressure in glaucoma<\/li>\n<\/ul>\n<h3>Side Effects<\/h3>\n<ul>\n<li>Caution client with night driving as medication can decrease visual acuity<\/li>\n<\/ul>\n<h3>Nursing Considerations<\/h3>\n<ul>\n<li>Apply pressure on lacrimal sac after instilling<\/li>\n<\/ul>\n<figure id=\"attachment_1134\" aria-describedby=\"caption-attachment-1134\" style=\"width: 587px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1134 size-full\" src=\"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/397\/2019\/10\/Picture1.jpg\" alt=\"\" width=\"587\" height=\"319\" srcset=\"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/397\/2019\/10\/Picture1.jpg 587w, https:\/\/opentextbc.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/397\/2019\/10\/Picture1-300x163.jpg 300w, https:\/\/opentextbc.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/397\/2019\/10\/Picture1-65x35.jpg 65w, https:\/\/opentextbc.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/397\/2019\/10\/Picture1-225x122.jpg 225w, https:\/\/opentextbc.ca\/nursingpharmacology\/wp-content\/uploads\/sites\/397\/2019\/10\/Picture1-350x190.jpg 350w\" sizes=\"auto, (max-width: 587px) 100vw, 587px\" \/><figcaption id=\"caption-attachment-1134\" class=\"wp-caption-text\">Figure 4.7a<\/figcaption><\/figure>\n<\/div>\n<\/div>\n<h3>Media Attributions<\/h3>\n<ul>\n<li>Figure 4.7a: Lacrimal Sac by OpenStax Microbiology is licensed under a <a class=\"internal\" href=\"https:\/\/creativecommons.org\/licenses\/by\/2.0\/\" rel=\"noopener\">CC BY 2.0 licence<\/a>.<\/li>\n<\/ul>\n<hr class=\"before-footnotes clear\" \/><div class=\"footnotes\"><ol><li id=\"footnote-175-1\">uCentral from Unbound Medicine. <a href=\"https:\/\/www.unboundmedicine.com\/ucentral\" rel=\"noopener noreferrer\">https:\/\/www.unboundmedicine.com\/ucentral<\/a> <a href=\"#return-footnote-175-1\" class=\"return-footnote\" aria-label=\"Return to footnote 1\">&crarr;<\/a><\/li><li id=\"footnote-175-2\">This work is a derivative of <a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/\" rel=\"noopener noreferrer\">Daily Med<\/a> by <a href=\"https:\/\/www.nlm.nih.gov\/\" rel=\"noopener noreferrer\">U.S. National Library of Medicine<\/a> in the <a class=\"internal\" href=\"https:\/\/creativecommons.org\/share-your-work\/public-domain\/\" rel=\"noopener noreferrer\">public domain<\/a>. <a href=\"#return-footnote-175-2\" class=\"return-footnote\" aria-label=\"Return to footnote 2\">&crarr;<\/a><\/li><\/ol><\/div>","protected":false},"author":90,"menu_order":7,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[50],"contributor":[],"license":[],"class_list":["post-175","chapter","type-chapter","status-publish","hentry","chapter-type-numberless"],"part":150,"_links":{"self":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/175","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/users\/90"}],"version-history":[{"count":8,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/175\/revisions"}],"predecessor-version":[{"id":1725,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/175\/revisions\/1725"}],"part":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/150"}],"metadata":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/175\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/media?parent=175"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=175"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/contributor?post=175"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/license?post=175"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}