{"id":328,"date":"2019-12-08T22:46:56","date_gmt":"2019-12-09T03:46:56","guid":{"rendered":"https:\/\/opentextbc.ca\/nursingpharmacology\/chapter\/6-13-erectile-agents\/"},"modified":"2022-07-13T20:23:50","modified_gmt":"2022-07-14T00:23:50","slug":"6-13-erectile-agents","status":"publish","type":"chapter","link":"https:\/\/opentextbc.ca\/nursingpharmacology\/chapter\/6-13-erectile-agents\/","title":{"raw":"6.13 Erectile Agents","rendered":"6.13 Erectile Agents"},"content":{"raw":"

Erectile Agents<\/h1>\r\nSildenafil (Viagra) is commonly known to treat erectile dysfunction. This medication was originally developed for improvement of pulmonary hypertension, but has been found to be useful for additional indications. However, clients taking this medication cannot take nitroglycerin due to severe hypotension.\r\n

Mechanism of Action<\/h2>\r\nSildenafil inhibits phosphodiesterase (PDE-5) in the pulmonary smooth muscle and corpus cavernosum. This allows for relaxation in the smooth muscle.\r\n

Indications for Use<\/h2>\r\nSildenafil is used in the treatment of pulmonary hypertension and erectile dysfunction.\r\n

Nursing Considerations Across the Lifespan<\/h2>\r\nPediatric clients have been shown to have an increase in mortality with sildenafil.\r\n\r\nDose adjustments are needed for clients with hepatic and renal impairment.\r\n\r\nUse cautiously with geriatric clients with decreased hepatic, renal, and cardiac functions.\r\n

Adverse\/Side Effects<\/h2>\r\nClients taking sildenafil may expect to experience hypotension, visual or hearing loss, priapism (male), headache, or vaso-occlusive crisis. If clients have priapism that lasts longer than 4 hours, they should seek medical attention.[footnote]This work is a derivative of Daily Med<\/a> by U.S. National Library of Medicine<\/a> in the public domain<\/a>. [\/footnote]\r\n

Client Education & Teaching<\/h2>\r\nClients should be instructed to take medications as directed and should seek immediate medical attention if chest pain occurs.\u00a0 Clients need education regarding the need to report priapism lasting longer than 4 hours or if they notice any dizziness or decrease in hearing ability.[footnote]uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral<\/a>[\/footnote]","rendered":"

Erectile Agents<\/h1>\n

Sildenafil (Viagra) is commonly known to treat erectile dysfunction. This medication was originally developed for improvement of pulmonary hypertension, but has been found to be useful for additional indications. However, clients taking this medication cannot take nitroglycerin due to severe hypotension.<\/p>\n

Mechanism of Action<\/h2>\n

Sildenafil inhibits phosphodiesterase (PDE-5) in the pulmonary smooth muscle and corpus cavernosum. This allows for relaxation in the smooth muscle.<\/p>\n

Indications for Use<\/h2>\n

Sildenafil is used in the treatment of pulmonary hypertension and erectile dysfunction.<\/p>\n

Nursing Considerations Across the Lifespan<\/h2>\n

Pediatric clients have been shown to have an increase in mortality with sildenafil.<\/p>\n

Dose adjustments are needed for clients with hepatic and renal impairment.<\/p>\n

Use cautiously with geriatric clients with decreased hepatic, renal, and cardiac functions.<\/p>\n

Adverse\/Side Effects<\/h2>\n

Clients taking sildenafil may expect to experience hypotension, visual or hearing loss, priapism (male), headache, or vaso-occlusive crisis. If clients have priapism that lasts longer than 4 hours, they should seek medical attention.[1]<\/sup><\/a><\/p>\n

Client Education & Teaching<\/h2>\n

Clients should be instructed to take medications as directed and should seek immediate medical attention if chest pain occurs.\u00a0 Clients need education regarding the need to report priapism lasting longer than 4 hours or if they notice any dizziness or decrease in hearing ability.[2]<\/sup><\/a><\/p>\n

  1. This work is a derivative of Daily Med<\/a> by U.S. National Library of Medicine<\/a> in the public domain<\/a>. ↵<\/a><\/li>
  2. uCentral from Unbound Medicine. https:\/\/www.unboundmedicine.com\/ucentral<\/a> ↵<\/a><\/li><\/ol><\/div>","protected":false},"author":90,"menu_order":13,"template":"","meta":{"pb_show_title":"on","pb_short_title":"","pb_subtitle":"","pb_authors":[],"pb_section_license":""},"chapter-type":[50],"contributor":[],"license":[],"class_list":["post-328","chapter","type-chapter","status-publish","hentry","chapter-type-numberless"],"part":268,"_links":{"self":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/328","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters"}],"about":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/types\/chapter"}],"author":[{"embeddable":true,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/users\/90"}],"version-history":[{"count":3,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/328\/revisions"}],"predecessor-version":[{"id":1284,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/328\/revisions\/1284"}],"part":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/parts\/268"}],"metadata":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapters\/328\/metadata\/"}],"wp:attachment":[{"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/media?parent=328"}],"wp:term":[{"taxonomy":"chapter-type","embeddable":true,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/pressbooks\/v2\/chapter-type?post=328"},{"taxonomy":"contributor","embeddable":true,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/contributor?post=328"},{"taxonomy":"license","embeddable":true,"href":"https:\/\/opentextbc.ca\/nursingpharmacology\/wp-json\/wp\/v2\/license?post=328"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}